Turning 21: Induction of miR-21 as a key switch in the inflammatory response
miR-21 is one of the most highly expressed members Wire Nut Connector of the small non-coding microRNA family in many mammalian cell types.Its expression is further enhanced in many diseased states including solid tumors, cardiac injury and inflamed tissue.Whilst the induction of miR-21 by inflammatory stimuli cells has been well documented in both